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A DISTINCTIVE SPECIALIZATION

Independent validation of clinical prediction models and AI systems

Objective evidence on whether a model performs, for whom, and whether it is ready to deploy — or still holding up after deployment.

What we evaluate

External & temporal validation

Testing performance on independent data, new sites and later time periods, not just the development sample.

Discrimination & calibration

AUROC, precision-recall, calibration curves and decision-curve analysis, reported to TRIPOD standards.

Subgroup & fairness analysis

Performance across patient groups, sites and settings, with clear reporting of where a model falls short.

Transportability

Why performance changes between health systems and populations, and what can be done about it.

Monitoring & drift

Post-deployment monitoring plans and recalibration or updating strategies as data and practice change.

Deployment readiness

Evidence packages that support go / no-go decisions, governance review and reporting to oversight bodies.

Who this is for

Health systems

Evaluating vendor or in-house models before and after go-live.

AI developers & life sciences

Independent evidence of performance for customers, regulators and publications.

Agencies & funders

Objective assessment of AI tools proposed or used in funded programs.

Areas of work

External & temporal validation

Methods for testing whether a prediction model holds up in a new site, population or period.

Deployment-risk methods

Developing methods to estimate how outcome risk may shift when a model is introduced into clinical use.

Methods research

Research on how the timing of clinical observations can bias early-warning signals, with a manuscript currently under peer review.

How an engagement works

1

Scope

A short conversation to understand your question, data and deadline.

2

Plan

A written analysis or evaluation plan with methods, deliverables and timeline.

3

Deliver

Analysis by senior specialists, with reproducible code and clear documentation.

4

Support

Help interpreting results, responding to reviewers and preparing outputs.

Common questions

Why independent validation?

Developers have an interest in favorable results. An independent evaluation gives decision-makers, regulators and reviewers evidence they can trust.

Do you need access to the model itself?

Not always. Many evaluations need only model outputs (risk scores) and outcomes on an evaluation dataset.

Which reporting standards do you follow?

We follow established reporting guidance for prediction models, such as TRIPOD and TRIPOD+AI, and tailor reporting to the audience.

Work with SmartDaaS

Tell us what you're working on.

SmartDaaS is a principal-led firm. Every engagement is directed by the principal and staffed with the senior specialists it needs from our network of biostatisticians, epidemiologists, health economists, data scientists and clinicians.

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